Buy N-Desethylprotonitazene (analgesic) Cas 168310594
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N-Desethylprotonitazene is a benzimidazole opioid with potent analgesic effects which has been sold as a designer drug. It was first identified in 2024 as an active metabolite of the closely related compound protonitazene,[1][2] and was found to have less potency than it while still being more potent than fentanyl.[3][4]
It was discovered in a drug sample from Chicago in June 2025.[3]
See also
Buy Butonitazene (opioid) Cas 95810-54-1
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N-Desethylprotonitazene is an opioid analgesic derivative of benzimidazole, an active …
N-Desethylprotonitazene is an opioid drug derivative of benzimidazole, an active metabolite of protonitazene, with a strong analgesic effect. This drug is a designer research substance and there is little data on its toxicological and pharmacological properties and dosage.
According to studies conducted in mice, this substance is an active agonist of opioid receptors and is about 20 times stronger than fentanyl when administered intravenously. The effects of exposure are similar to other strong opioids derived from benzimidazole, such as sedative and hypnotic effects, analgesia, hypnotic effect and euphoria. Buy N-Desethylprotonitazene (analgesic) Cas 168310594
Unique properties
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– Unlike most opioids, N-Desethylprotonitazene has a unique pharmacological profile. The action of this drug makes it a unique research tool for exploring potential therapeutic benefits and side effects.Description
N-Desethylprotonitazene is an opioid drug derivative of benzimidazole, an active metabolite of protonitazene, with a strong analgesic effect. This drug is a designer research substance and there is little data on its toxicological and pharmacological properties and dosage.
Chemistry
N-Desethylprotonitazene is a metabolite of protonitazene and has a related structure.
Pharmacology, Pharmacodynamic
According to studies conducted in mice, this substance is an active agonist of opioid receptors and is about 20 times stronger than fentanyl when administered intravenously. The effects of exposure are similar to other strong opioids derived from benzimidazole, such as sedative and hypnotic effects, analgesia, hypnotic effect and euphoria.
Side effects
In chemical studies and tests, it is necessary to approach the dosages of this substance as carefully as possible, since high dosages of this substance, since high dosages of this substance can cause respiratory depression, vomiting, itching, delirium.
Application in medicine
N-Desethylprotonitazene is a designer research drug and has never been used for medical purposes.
Dosage
The exact dosage is not known, due to the lack of proper medical research.
Legal status
The substance is relatively new and has an unclear legal status.
Disclaimer of liability
N-Desethylprotonitazene is intended only as a substance for scientific and research purposes in special laboratory conditions in compliance with all standards and safety measures.
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Technical Information:
Product Name N-Desethylprotonitazene HCL
Synonyms N-Desethyl Protonitazene
IUPAC Name N-ethyl-2-(5-nitro-2-(4-propoxybenzyl)-1H-benzo[d]imidazol-1-yl)ethan-1-amine
CAS Number
Molecular Formula C21H26N4O3
Formula Weight 382.464 g•mol−1
InChi Code InChI=1S/C21H26N4O3.ClH/c1-3-13-28-18-8-5-16(6-9-18)14-21-23-19-15-17(25(26)27)7-10-20(19)24(21)12-11-22-4-2;/h5-10,15,22H,3-4,11-14H2,1-2H3;1H
InChi Key XSOYNCRLLHSYMF-UHFFFAOYSA-N
SMILES CCCOC(C=C1)=CC=C1CC2=NC3=CC([N+]([O-])=O)=CC=C3N2CCNCC.Cl
Solubility
DMF: 20 mg/ml
DMSO: 14 mg/ml
Ethanol: Slightly soluble
PBS (pH 7.2): 0.3 mg/ml
Formulation A solid
Purity ≥98%
Disclaimer of liability
N-Desethylprotonitazene is intended only as a substance for scientific and research purposes in special laboratory conditions in compliance with all standards and safety measures.
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Molecular Formula: C 21 H 26 N 4 O 3 • HCl
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Product Name: N-desethyl Protonitazene
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Molecular Weight: 418.9
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N-desethyl Protonitazene (hydrochloride) | Cayman Chemical
N-desethyl Protonitazene (hydrochloride): An Analytical Reference Standard. Purity: ≥98%.
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