Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

MMDA, also known as 3-methoxy-4,5-methylenedioxyamphetamine or as 5-methoxy-MDA, is a psychedelic and entactogen of the amphetamine family.^[1]

In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists MMDA’s dose as 100 to 250 mg orally and its duration as “moderate”.^[1] Its onset is described as 20 to 45 minutes.^[1] The effects of MMDA have been reported to include relaxation, time dilation, empathy, passivity, compassion, changes in music perception, closed-eye visuals such as geometric patterns, open-eye visuals, dream-like states described as “brain movies”, and an afterglow.^[1][3] It has been said to be gentler than certain other psychedelics.^[1] The drug is said to have similar effects to MDA, but to be to some extent more psychedelic in comparison.^{[3]  Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0}

Side effects of MMDA have been reported to include restlessness, cold sensations, shivering, nausea, abdominal cramps, disorientation, social withdrawal, feeling ill, and anxiety.^[1]

MMDA has been shown to act as a non-neurotoxic serotonin releasing agent, with no effects on release of dopamine or probably norepinephrine,^[4] and as a serotonin 5-HT_2A receptor agonist.^[5] The latter property is thought to be responsible for its psychedelic effects, whereas the former action may be involved in its entactogenic effects.^[4][5]

MMDA has been found to be formed from myristicin, a component of nutmeg, in rabbits and rats.^[1][6] However, MMDA could not be detected with nutmeg misuse in a human.^[7]

The chemical synthesis of MMDA has been described.

13674-05-0

• 

• Basic information

  1. Product Name: MMDA
  2. Synonyms: MMDA;1-(3-Methoxy-4,5-methylenedioxyphenyl)-2-propaneamine;5-Methoxy-3,4-methylenedioxyamphetamine;5-Methyl-3,4-methylenedioxyamphetamine;7-Methoxy-α-methyl-1,3-benzodioxole-5-ethanamine;YQYUWUKDEVZFDB-UHFFFAOYSA-N
  3. CAS NO:13674-05-0
  4. Molecular Formula: C11H15 N O3
  5. Molecular Weight: 209.24
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 13674-05-0.mol

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 317.1°Cat760mmHg
  3. Flash Point: 154.1°C
  4. Appearance: /
  5. Density: 1.175g/cm³
  6. Vapor Pressure: 0.000393mmHg at 25°C
  7. Refractive Index: N/A
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. PKA: 9.66±0.10(Predicted)
  11. CAS DataBase Reference: MMDA(CAS DataBase Reference)
  12. NIST Chemistry Reference: MMDA(13674-05-0)
  13. EPA Substance Registry System: MMDA(13674-05-0)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 13674-05-0(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

13674-05-0 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn’t provide relevant sales information.

13674-05-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 13674-05-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,6,7 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13674-05:
(7*1)+(6*3)+(5*6)+(4*7)+(3*4)+(2*0)+(1*5)=100
100 % 10 = 0
So 13674-05-0 is a valid CAS Registry Number.

InChI:InChI=1/C11H15NO3.ClH/c1-7(12)3-8-4-9(13-2)11-10(5-8)14-6-15-11;/h4-5,7H,3,6,12H2,1-2H3;1H

13674-05-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) – Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-amine

1.2 Other means of identification

Product number	– Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0
Other names	2-(7-methoxy-benzo[1,3]dioxol-5-yl)-1-methyl-ethylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

1.4 Supplier’s details

Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0
Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0
Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0
Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

1.5

Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	– Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0
Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

More Details:13674-05-0 SDS

13674-05-0Upstream product

• 97383-34-14-methoxy-6-(2-nitro-propenyl)-benzo[1,3]dioxole 
• 607-91-0myristicin 
• 157426-98-72-bromo-1-(3-methoxy-4,5-methylenedioxyphenyl)propane 

13674-05-0Downstream Products

13674-05-0Relevant academic research and scientific papers

Purification and Characterization of Anabaena flos-aquae Phenylalanine Ammonia-Lyase as a Novel Approach for Myristicin Biotransformation

Abdel-Ghany, Afaf E.,Abdelaziz, Sahar,Arafa, Asmaa M.,El-Ayouty, Yassin,El-Dahmy, Samih I.,El-Sayed, Ashraf S. A.

, p. 622 – 632 (2020/05/08)

Phenylalanine ammonia-lyase (PAL) catalyzes the reversible deamination of phenylalanine to cinnamic acid and ammonia. Algae have been considered as biofactories for PAL production, however, biochemical characterization of PAL and its potency for myristicin biotransformation into MMDA (3-methoxy-4, 5-methylenedioxyamphetamine) has not been studied yet. Thus, PAL from Anabaena flos-aquae and Spirulina platensis has been purified, comparatively characterized and its affinity to transform myristicin was assessed. The specific activity of purified PAL from S. platensis (73.9 μmol/mg/min) and A. flos-aquae (30.5 μmol/mg/min) was increased by about 2.9 and 2.4 folds by gel-filtration comparing to their corresponding crude enzymes. Under denaturing-PAGE, a single proteineous band with a molecular mass of 64 kDa appeared for A. flos-aquae and S. platensis PAL. The biochemical properties of the purified PAL from both algal isolates were determined comparatively. The optimum temperature of S. platensis and A. flos-aquae PAL for forward or reverse activity was reported at 30oC, while the optimum pH for PAL enzyme isolated from A. flos-aquae was 8.9 for forward and reverse activities, and S. platensis PAL had maximum activities at pH 8.9 and 8 for forward and reverse reactions, respectively. Luckily, the purified PALs have the affinity to hydroaminate the myristicin to MMDA successfully in one step. Furthermore, a successful method for synthesis of MMDA from myristicin in two steps was also established. Gas chromatography-mass spectrometry (GC-MS) analysis was conducted to track the product formation.

MMDA

Alias: 3-Methoxy-4,5-methylenedioxyphenylisopropylam; MMDA; 5-Methoxy-3,4-methylenedioxyamphetamine; 13674-05-0; (+-)-MMDA; 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine; DEA No. 7401; 3-Methoxy-4,5-methylenedioxyphenylisopropylamine; Amphetamine, 3,4-methylenedioxy-5-methoxy; (+-)-MMDA; MMDA

Cat No.:V19418Purity: ≥98%

COAProduct DataInstructions for useSDS

MMDA is a novel and potent psychedelic and entactogen drug

MMDA Chemical StructureCAS No.: 13674-05-0
Product category: New1

 This product is for research use only, not for human use. We do not sell to patients.

Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0
Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0
Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0
Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0	Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

 

Product Description

MMDA is a novel and potent psychedelic and entactogen drug

Biological Activity I Assay Protocols (From Reference)

Toxicity/Toxicokinetics

The mouse LD50 was not reported at 150 mg/kg. (Experientia., 20(366), 1964 [PMID:5855670])

Additional Infomation

MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, belongs to the amphetamine class of drugs and possesses stimulant and hallucinogenic properties. It is also a hallucinogen and mood enhancer. MMDA is structurally similar to the psychopharmacologically active essential oils elemol and myristole found in nutmeg. MMDA’s effects include euphoria and warmth, as well as realistic visual experiences with eyes closed. Drug Indications MMDA is a recreational drug. Currently, it has no medical use and is classified as a Category 1 controlled substance in the United States. Mechanism of Action The mechanism by which MMDA produces hallucinogenic effects is not fully understood. There are currently no reports on the pharmacokinetics or metabolism of MMDA in humans. Based on its structural relationship with other similar drugs with known pharmacological effects, MMDA may have multiple mechanisms of action, possibly acting as a 5HT2A agonist like hallucinogenic amphetamines such as DOM, or releasing serotonin by reversing the direction of the serotonin reuptake transporter, similar to MDMA.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Physicochemical Properties

Molecular Formula	C11H15NO3
Exact Mass	209.105
CAS #	13674-05-0
Related CAS #	60676-84-8 (hydrochloride)
PubChem CID	26175
Appearance	Typically exists as solid at room temperature
LogP	1.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	15
Complexity	212
Defined Atom Stereocenter Count	0
InChi Key	YQYUWUKDEVZFDB-UHFFFAOYSA-N
InChi Code	InChI=1S/C11H15NO3/c1-7(12)3-8-4-9(13-2)11-10(5-8)14-6-15-11/h4-5,7H,3,6,12H2,1-2H3
Chemical Name	1-(7-methoxy-1,3-benzodioxol-5-yl)propan-2-amine
Synonyms	3-Methoxy-4,5-methylenedioxyphenylisopropylam; MMDA; 5-Methoxy-3,4-methylenedioxyamphetamine; 13674-05-0; (+-)-MMDA; 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine; DEA No. 7401; 3-Methoxy-4,5-methylenedioxyphenylisopropylamine; Amphetamine, 3,4-methylenedioxy-5-methoxy; (+-)-MMDA; MMDA
HS Tariff Code	2934.99.9001
Storage	Powder      -20°C    3 years 4°C     2 years In solvent   -80°C    6 months -20°C    1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Solubility Data

Solubility (In Vitro)

May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples

Solubility (In Vivo)

Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples. Injection Formulations (e.g. IP/IV/IM/SC) Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] *Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Injection Formulation 5: 2-Hydroxypropyl-β-cyclodextrin : Saline = 50 : 50 (i.e. 500 μL 2-Hydroxypropyl-β-cyclodextrin → 500 μL Saline) Injection Formulation 6: DMSO : PEG300 : castor oil : Saline = 5 : 10 : 20 : 65 (i.e. 50 μL DMSO → 100 μLPEG300 → 200 μL castor oil → 650 μL Saline) Injection Formulation 7: Ethanol : Cremophor : Saline = 10： 10 : 80 (i.e. 100 μL Ethanol → 100 μL Cremophor → 800 μL Saline) Injection Formulation 8: Dissolve in Cremophor/Ethanol (50 : 50), then diluted by Saline Injection Formulation 9: EtOH : Corn oil = 10 : 90 (i.e. 100 μL EtOH → 900 μL Corn oil) Injection Formulation 10: EtOH : PEG300：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL EtOH → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Oral Formulations Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More Oral Formulation 3: Dissolved in PEG400 Oral Formulation 4: Suspend in 0.2% Carboxymethyl cellulose Oral Formulation 5: Dissolve in 0.25% Tween 80 and 0.5% Carboxymethyl cellulose Oral Formulation 6: Mixing with food powders   Note: Please be aware that the above formulations are for reference only. InvivoChem strongly recommends customers to read literature methods/protocols carefully before determining which formulation you should use for in vivo studies, as different compounds have different solubility properties and have to be formulated differently.  (Please use freshly prepared in vivo formulations for optimal results.)

Calculator

• Molarity Calculator
• Dilution Calculator
• Molecular Weight Calculator
• Reconstitution Calculator

Mass

pgngμgmggkg

Concentration

pMnMμMmMM

Volume

nLμLmLL

Molecular Weight*

CalculateReset

Molarity Calculator allows you to calculate the mass, volume, and/or concentration required for a solution, as detailed below:

• Calculate the Mass of a compound required to prepare a solution of known volume and concentration
• Calculate the Volume of solution required to dissolve a compound of known mass to a desired concentration
• Calculate the Concentration of a solution resulting from a known mass of compound in a specific volume

ECSTASY HAPTENS AND IMMUNOGENS

–

Page/Page column 55, (2010/02/12)

Methods, compositions and kits are disclosed. Enzyme conjugates of Formula (I) are employed in assays for the determination of an methylenedioxyamphetamine, a methylene-dioxyethamphetamine, and/or a methylenedioxymethamphetamine. Immunogenic conjugates of Formula I are employed to prepare antibodies for an methylenedioxyamphetamine, a methylenedioxyethamphetamine, and/or for a methylene- dioxymethamphetamine for use in assays for the determination of an methylenedioxyamphetamine, a methyl enedioxyethamphetamine, and/or a methylene-dioxymethamphetamine. The enzyme conjugates may also be employed to screen antibodies for use in such methods.

1. MMDA | CS-O-42759 | CAS 13674-05-0 | Clearsynth

   Buy MMDA from Clearsynth. View CAT No. CS-O-42759, CAS No. 13674-05-0, molecular formula, molecular weight, stock status, …
2. MMDA CAS#: 13674-05-0 – ChemicalBook

   3-Methoxy-MDA Hydrochloride is an analog of 3,4-Methylenedioxy Amphetamine (M303965, HCl salt) which is a metabolite of …

   • CAS: 13674-05-0
   • MW: 209.24

   • MF: C11H15NO3
   • Product Name: MMDA
3. MMDA | psychedelic and entactogen drug | CAS# 13674-05-0

   MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, belongs to the amphetamine class of drugs and possesses stimulant and …

   • Reviews: 1
   • Exact Mass: 209.105

   • CAS #: 13674-05-0
   • Molecular Formula: C11H15NO3
4. cas 13674-05-0 – HENAN REFORTUNE INDUSTRIAL CO.,LTD

   Nov 14, 2022 · CAS No. 13674-05-0 Chemical Name: MMDA Synonyms MMDA;YQYUWUKDEVZFDB-UHFFFAOYSA-N;5-Methyl …

5. MMDA | 13674-05-0 – ChemicalBook

    MMDA (CAS 13674-05-0) information, including chemical properties, structure, melting point, boiling point, density, …

6. 3-Methoxy-4,5-methylenedioxyamphetamine – PubChem

   3-Methoxy-4,5-methylenedioxyamphetamine | C11H15NO3 | CID 26175 – structure, chemical names, physical and chemical …

7. MMDA,13674-05-0 – LookChemical.com

   MMDA,13674-05-0 – Buyers Guide for Chemicals is a directory of chemicals, chemical suppliers and producers. More than 140,000 …

8. Cas 13674-05-0,MMDA | lookchem

   Algae have been considered as biofactories for PAL production, however, biochemical characterization of PAL and its potency for …

9. Where to Buy CAS No.: 60676-84-8 | MMDA (hydrochloride)

   MMDA (Hydrochloride), or 3-methoxy-4,5-methylenedioxyamphetamine, is a psychoactive compound structurally related to …

10. MMDA CAS#: 13674-05-0 • ChemWhat | Database of Chemicals

    MMDA CAS#: 13674-05-0; ChemWhat Code: 139992