Buy Methamnetamine (methylnaphetamine) Cas 1178720-66-5

Methamnetamine (also known as methylnaphetamine, MNA, MNT, MNAP, PAL-1046, and MY-10) is a triple monoamine releasing agent of the amphetamine and naphthylaminopropane families. It is the N-methyl analog of the non-neurotoxic experimental drug naphthylaminopropane and the naphthalene analog of methamphetamine.^[2]^[3]^[4] It has been sold online as a designer drug between 2015 and 2016.^[5]^[6]^[7]

Pharmacology

Pharmacodynamics

Methamnetamine acts as a releasing agent of serotonin, norepinephrine, and dopamine, with EC₅₀ values of 13 nM, 34 nM, and 10 nM, respectively.^[2] It is also a lower-potency partial agonist of the serotonin 5-HT_2A receptor.^[8]

Monoamine release of methamnetamine and related agents (EC₅₀Tooltip Half maximal effective concentration, nM)
Compound	NETooltip Norepinephrine	DATooltip Dopamine	5-HTTooltip Serotonin	Ref
d-Amphetamine	6.6–10.2	5.8–24.8	698–1,765	^[9]^[10]^[11]^[12]^[13]
Naphthylaminopropane (NAP; PAL-287)	11.1	12.6	3.4	^[14]^[11]
d-Methamphetamine	12.3–14.3	8.5–40.4	736–1,292	^[9]^[15]^[11]^[13]
Methylnaphthylaminopropane (MNAP; PAL-1046)	34	10	13	^[16]^[17]
l-Methcathinone	13.1	14.8	1,772	^[18]^[12]
2-Naphthylmethcathinone (BMAPN; βk-MNAP)	94% at 10 μM	34	27	^[19]^[20]
d-Ethylamphetamine	28.8	44.1	333.0	^[21]^[22]
Ethylnaphthylaminopropane (ENAP; PAL-1045)	137	46 ^a	12 ^a	^[16]
Phenmetrazine	29–50.4	70–131	7,765–>10,000	^[23]^[11]^[24]^[25]
Naphthylmetrazine (PAL-704)	203	111	RI (105)	^[25]
Notes: The smaller the value, the more strongly the drug releases the neurotransmitter. The assays were done in rat brain synaptosomes and human potencies may be different. See also Monoamine releasing agent § Activity profiles for a larger table with more compounds. Footnotes: ^a ENAPTooltip Ethylnaphthylaminopropane is a partial releaser of serotonin (E_maxTooltip maximal efficacy = 66%) and dopamine (E_max = 78%). Refs:^[26]^[27]

Society and culture

Legal status

Methamnetamine is illegal in Japan.^[28]

Methamnetamine

CAS Registry Number:: 1178720-66-5
Synonyms:: Methamnetamine;Methylnaphetamine;N-Methyl-PAL-287;CAS64BB01B;PAL-1046;UNII-CAS64BB01B;1178720-66-5;2-Naphthaleneethanamine, N,alpha-dimethyl-;Methamnetamine (hydrochloride);SCHEMBL10023024;DTXSID801032850;2-NAPHTHALENEETHANAMINE, N,.ALPHA.-DIMETHYL-;Q21098978
Molecular Formula:: C14H17N
Molecular Weight:: 199.29
EINECS:
Melting Point:
Solubility:

Methamnetamine

Methamnetamine hydrochloride (Synonyms: PAL-1046 hydrochloride) Methamnetamine (PAL-1046) hydrochloride is an amphetamine-based psychoactive substance. Methamnetamine hydrochloride causes excessive release of serotonin. For research use only. We do not sell to patients. CAS No.:2748623-12-1 Formula:C₁₄H₁₈ClN Molecular Weight:235.75 Storage: Please store the product under the recommended conditions in the Certificate of Analysis. Methamnetamine structure

CAS No:1178720-66-5
Formula:C14H17N
Chemical Name:Methamnetamine
Synonyms:
Methamnetamine;UNII-CAS64BB01B;Methylnaphetamine;CAS64BB01B;N-Methyl-PAL-287;SCHEMBL10023024;PAL-1046;2-Naphthaleneethanamine, N,alpha-dimethyl-;Q21098978;1178720-66-5
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Methamnetamine Basic Attributes

Molecular Weight：

199.29

Exact Mass：

199.136099547

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