Buy Mepyramine (pyrilamine) Cas 91-84-9
Mepyramine, also known as pyrilamine, is a first-generation antihistamine, targeting the H1 receptor as an inverse agonist.[1] Mepyramine rapidly permeates the brain, often causing drowsiness.[2] It is often sold as a maleate salt, pyrilamine maleate.
The medication has negligible anticholinergic activity, with 130,000-fold selectivity for the histamine H1 receptor over the muscarinic acetylcholine receptors (for comparison, diphenhydramine had 20-fold selectivity for the H1 receptor).[3]
It was patented in 1943 and came into medical use in 1949.[4] It was marketed under the names Histadyl, Histalon, Neo-Antergan, Neo-Pyramine, and Nisaval.[5] In the 1960s and 70s it was a very common component in over-the-counter sleep aids such as Alva-Tranquil, Dormin, Sedacaps, Sominex, Nytol, and many others.[5] The US Food and Drug Administration (FDA) included it in the list of chemicals and compounds barred from use in over-the-counter (OTC) nighttime sleep aid products in 1989.[6]
It is used in over-the-counter combination products to treat the common cold and menstrual symptoms such as Midol Complete.[7] It is also the active ingredient of the topical antihistamine creams Anthisan[8] and Neoantergan[1] sold for the treatment of insect bites, stings, and nettle rash.
PYRILAMINE
N’-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N’-pyridin-2-ylethane-1,2-diamine
Mepyramine is an ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group. It has a role as a H1-receptor antagonist. It is an ethylenediamine derivative and an aromatic ether.
Source: ChEBI
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MEPYRAMINE
Mepyramine is a research-grade compound used in advanced pharmaceutical and biochemical studies. Chemical & Pharmacological Characteristics Experimental behavior is governed by solubility, stability, ionization state, and matrix interactions. Proper formulation control is required for reproducible results. Mechanism of Action No single universal receptor mechanism is assumed; observed effects are context- and concentration-dependent. It is primarily applied to investigate compound-specific mechanisms, physicochemical behavior, and analytical or formulation-relevant characteristics under controlled laboratory conditions. Only GMP materials will be supplied, logistics all according to GDP.
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PYRILAMINE | 91-84-9 – ChemicalBook
PYRILAMINE (CAS 91-84-9) information, including chemical properties, structure, melting point, boiling point, …
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Hazard statements: H302
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Signal word: Warning
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Precautionary statements: P280-P305+P351+P338
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Symbol (GHS): GHS07
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PYRILAMINE CAS 91-84-9 — Buy Online | Chem-Gold
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CAS No : 91-84-9| Product Name : Mepyramine – API| Chemical Name …
Mepyramine is an over-the-counter drug which is a first generation H1 receptor antagonist and it is used in treatment of insect bites, …
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CAS Number: 91-84-9
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Chemical name: Mepyramine
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Catalogue number: PA 13 19000
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Similar Products: 59-33-6 (Maleate Salt)
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Mepyramine Supplier | CAS 91-84-9 | AOBIOUS
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BUY MEPYRAMINE (GMP grade) – Global API Supplier
Mepyramine is a research-grade compound used in advanced pharmaceutical and biochemical studies. Chemical & Pharmacological …
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91-84-9 | MFCD00023451 | PYRILAMINE
A2B Chem-AY09951; PYRILAMINE 99%; CAS Number: 91-84-9; MDL Number: MFCD00023451; Formula: C17H23N3O; find …
CAS 91-84-9 | PYRILAMINE supply – Guidechem Chemical Network
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91-84-9|N1- (4-Methoxybenzyl)-N2,N2-dimethyl-N1- (pyridin-2
Mepyramine Synonyms:NSC-13136 N1- (4-Methoxybenzyl)-N2,N2-dimethyl-N1- (pyridin-2-yl)ethane-1,2-diamine * Cold-chain …
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