Buy Isotonitazepyne (N-pyrrolidino-isotonitazene- NPI) Cas 3053113-12-2
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Isotonitazepyne (N-pyrrolidino-isotonitazene, NPI) is a benzimidazole derivative with potent opioid effects, which has been sold as a designer drug over the internet. Its in vitro potency is approximately 1000 times that of morphine.[1] One sample of counterfeit oxycodone pills were found to contain between 3.3 and 3.5 mg of NPI per pill and no oxycodone.[2]
Timeline of detections
NPI was first identified in the UK in August 2024 by WEDINOS as samples W054816 and W057074,[3][4] then the full chemical characterisation and first literature reported sample was provided by CanTEST in Australia in September 2024,.[5][2] NPI was later detected in the Netherlands in May 2025,[6] and in Finland in early 2025.[7]
Legal status
This section is not exhaustive and does not include information for all countries with laws covering isotonitazepyne.
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