Buy MMDA (3-methoxy-4-5-methylenedioxyamphetamine) Cas 13674-05-0

MMDA, also known as 3-methoxy-4,5-methylenedioxyamphetamine or as 5-methoxy-MDA, is a psychedelic and entactogen of the amphetamine family.^[1]

In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists MMDA’s dose as 100 to 250 mg orally and its duration as “moderate”.^[1] Its onset is described as 20 to 45 minutes.^[1] The effects of MMDA have been reported to include relaxation, time dilation, empathy, passivity, compassion, changes in music perception, closed-eye visuals such as geometric patterns, open-eye visuals, dream-like states described as “brain movies”, and an afterglow.^[1][3] It has been said to be gentler than certain other psychedelics.^[1] The drug is said to have similar effects to MDA, but to be to some extent more psychedelic in comparison.^[3]

Side effects of MMDA have been reported to include restlessness, cold sensations, shivering, nausea, abdominal cramps, disorientation, social withdrawal, feeling ill, and anxiety.^[1]

MMDA has been shown to act as a non-neurotoxic serotonin releasing agent, with no effects on release of dopamine or probably norepinephrine,^[4] and as a serotonin 5-HT_2A receptor agonist.^[5] The latter property is thought to be responsible for its psychedelic effects, whereas the former action may be involved in its entactogenic effects.^[4][5]

MMDA has been found to be formed from myristicin, a component of nutmeg, in rabbits and rats.^[1][6] However, MMDA could not be detected with nutmeg misuse in a human.^[7]

The chemical synthesis of MMDA has been described.^[1]