Buy Seproxetine ((S)-norfluoxetine) Cas 126924-38-7

Buy Seproxetine ((S)-norfluoxetine) Cas 126924-38-7

Buy Seproxetine ((S)-norfluoxetine) Cas 126924-38-7

Seproxetine, also known as (S)-norfluoxetine, is a selective serotonin reuptake inhibitor (SSRI).^[1][2] It is the main active metabolite of the widely used antidepressant fluoxetine;^[3] it is nearly 4 times more selective for stimulating neurosteroid synthesis relative to serotonin reuptake inhibition than fluoxetine.^[4] It is formed through the demethylation, or removal of a methyl group, of fluoxetine.^[5] Seproxetine is both an inhibitor of serotonin and dopamine transporters, 5-HT_2A and 5-HT_2C receptors.^[6] It was being investigated by Eli Lilly and Company as an antidepressant; however, it causes cardiac arrhythmia by blocking the KvLQT1 protein, which is responsible for the management of the QT interval. This is the time it takes for the heart to contract and recover.^[7] Due to this, development of the medication was discontinued.^[1] Efficacy testing found that the drug was equivalent to fluoxetine, but sixteen times more powerful than the R enantiomer of norfluoxetine.

(S)-3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine

Synonym(s):

(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine

Select a Size

Change View

Size/SKU	Availability	Price
2.5 mg AABH303716C4-2.5MG	Ships in 21 days – from Aldrich Partner.	€817.32
25 mg AABH303716C4-25MG	Ships in 21 days – from Aldrich Partner.	€2,320.89

About This Item

Linear Formula:

C16H16O1N1F3

CAS Number:

126924-38-7

Molecular Weight:

295.3

MDL number:

MFCD00872148

AABH303716C4-2.5MG

Vendor SKU: AA000TEZ-2.5MG

---

---

(S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE is a chiral compound that is a metabolite of Fluoxetine, a selective serotonin reuptake inhibitor (SSRI) used as an antidepressant. It is also a stereoselective inhibitor of serotonin re-uptake and phosphodiesterase. This pale yellow oil is a promising candidate for pharmaceutical applications due to its potential antidepressant properties.

126924-38-7

Post Buying Request

• 

• Basic information

  1. Product Name: (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE
  2. Synonyms: (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE;Seproxetine [inn];Unii-25co3X0R31;(S)-Norfluoxetine
  3. CAS NO:126924-38-7
  4. Molecular Formula: C₁₆H₁₆F₃NO
  5. Molecular Weight: 295.2995496
  6. EINECS: N/A
  7. Product Categories: Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Metabolites & Impurities;Pharmaceuticals;Amines
  8. Mol File: 126924-38-7.mol

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 381.1°C at 760 mmHg
  3. Flash Point: 184.3°C
  4. Appearance: /
  5. Density: 1.204g/cm³
  6. Vapor Pressure: 5.21E-06mmHg at 25°C
  7. Refractive Index: 1.525
  8. Storage Temp.: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
  9. Solubility: N/A
  10. CAS DataBase Reference: (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE(CAS DataBase Reference)
  11. NIST Chemistry Reference: (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE(126924-38-7)
  12. EPA Substance Registry System: (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE(126924-38-7)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 126924-38-7(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

126924-38-7 Suppliers

Recommended suppliers

• Product
• FOB Price
• Min.Order
• Supply Ability
• Supplier
• Contact Supplier

• (S)-Norfluoxetine;126924-38-7Cas No: 126924-38-7
• No Data
• 10 Metric Ton
• Metric Ton/Day
• Amadis Chemical Co., Ltd.
• Contact Supplier

• Benzenepropanamine, g-[4-(trifluoromethyl)phenoxy]-, (gS)-Cas No: 126924-38-7
• No Data
• No Data
• 5
• Hangzhou J&H Chemical Co., Ltd.
• Contact Supplier

• (S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamineCas No: 126924-38-7
• USD $ 1.9-2.9 / Gram
• 100 Gram
• 1000 Metric Ton/Month
• Chemlyte Solutions
• Contact Supplier

• (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINECas No: 126924-38-7
• No Data
• No Data
• No Data
• BOC Sciences
• Contact Supplier

• (S)-NorfluoxetineCas No: 126924-38-7
• No Data
• No Data
• No Data
• Shanghai Shinso-pharm Technology Co. , Ltd.
• Contact Supplier

• (S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamineCas No: 126924-38-7
• No Data
• No Data
• No Data
• Nanjing Norris Pharm Technology Co., Ltd.
• Contact Supplier

• (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINECas No: 126924-38-7
• No Data
• No Data
• No Data
• Skyrun Industrial Co.,Ltd
• Contact Supplier

• (S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamineCas No: 126924-38-7
• No Data
• No Data
• No Data
• Hunan Longxianng Runhui Trading Co.,Ltd
• Contact Supplier

126924-38-7 Usage

Uses

Used in Pharmaceutical Industry:
(S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE is used as a potential antidepressant for treating depression and related mood disorders. As a metabolite of Fluoxetine, it exhibits the ability to selectively inhibit serotonin reuptake, thereby increasing the availability of serotonin in the synaptic cleft and promoting a more balanced mood.
Additionally, as a stereoselective inhibitor of phosphodiesterase, it may contribute to the modulation of intracellular signaling pathways, which could further enhance its antidepressant effects.
Used in Research Applications:
In the field of neuroscience and psychopharmacology, (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE serves as a valuable research tool for studying the mechanisms of action of SSRIs and their metabolites. Its stereoselective properties allow for the investigation of the role of enantiomers in the pharmacological effects of these drugs, potentially leading to the development of more effective and targeted antidepressant therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 126924-38-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,9,2 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 126924-38:
(8*1)+(7*2)+(6*6)+(5*9)+(4*2)+(3*4)+(2*3)+(1*8)=137
137 % 10 = 7
So 126924-38-7 is a valid CAS Registry Number.

InChI:InChI=1/C16H16F3NO/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12/h1-9,15H,10-11,20H2/t15-/m0/s1

126924-38-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) – Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	(3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine

1.2 Other means of identification

Product number	–
Other names	UNII-25CO3X0R31

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier’s details

1.5 Emergency phone number

Emergency phone number

(S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE(126924-38-7) CAS Registry Number: 126924-38-7 Synonyms: Benzenepropanamine,g-[4-(trifluoromethyl)phenoxy]-,(S)-;(S)-3-(4-Trifluoromethylphenoxy)-3-phenylpropylamine;(S)-Norfluoxetine;Seproxetine; Molecular Formula: C16H16 F3 N O Molecular Weight: 295.304 EINECS: CAS No.:126924-38-7 Name: (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE

(S)-Norfluoxetine (S)-Norfluoxetine structure CAS No. 126924-38-7 Chemical Name: (S)-Norfluoxetine Synonyms Unii-25co3X0R31;(S)-Norfluoxetine;Seproxetine [inn];(S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE;(3S)-3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]-1-Propanamine;Benzenepropanamine, γ-[4-(trifluoromethyl)phenoxy]-, (γS)-;1-[(1S)-3-Amino-1-phenylpropoxy]-4-(trifluoromethyl)benzene CBNumber: CB21009279 Molecular Formula: C16H16F3NO Molecular Weight: 295.2995496 MDL Number: MFCD00872148 MOL File: 126924-38-7.mol MSDS File: SDS TDS File: TDS Last updated:2026-04-24 14:58:18 Product description Number Pack Size Price (S)-Norfluoxetine >95%(HPLC) TRC-N681095-25MG 25mg $1965 (S)-Norfluoxetine >95%(HPLC) TRC-N681095-2.5MG 2.5mg $253 S-Norfluoxetine 018509 2.5mg $509 (3S)-3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]-1-Propanamine FP95603 1mg $900 (3S)-3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]-1-Propanamine FP95603 2mg $900 More product size Request For Quotation (S)-Norfluoxetine Properties Boiling point 381.1±42.0 °C(Predicted) Density 1.204±0.06 g/cm3(Predicted) storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere solubility Chloroform (Slightly), Methanol (Slightly) form Oil pka 9.05±0.13(Predicted) color Clear Colourless to Pale Yellow FDA UNII 25CO3X0R31 EPA Substance Registry System Benzenepropanamine, .gamma.-[4-(trifluoromethyl)phenoxy]-, (.gamma.S)- (126924-38-7) (S)-Norfluoxetine price Manufacturer Product number Product description CAS number Packaging Price Updated Buy TRC TRC-N681095-25MG (S)-Norfluoxetine >95%(HPLC) 126924-38-7 25mg $1965 2026-06-03 Buy TRC TRC-N681095-2.5MG (S)-Norfluoxetine >95%(HPLC) 126924-38-7 2.5mg $253 2026-06-03 Buy Usbiological 018509 S-Norfluoxetine 126924-38-7 2.5mg $509 2026-06-03 Buy Biosynth FP95603 (3S)-3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]-1-Propanamine 126924-38-7 1mg $900 2026-06-04 Buy Biosynth FP95603 (3S)-3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]-1-Propanamine 126924-38-7 2mg $900 2026-06-04 Buy (S)-Norfluoxetine Chemical Properties, Uses, Production Chemical Properties Pale Yellow Oil Uses (S)-Norfluoxetine is a labelled Fluoxetine (F597100) derivative,it is a stereoselective inhibitorof serotonin re-uptake and phosphodiesterase. It is used as a potential antidepressants. Uses A metabolite of Fluoxetine (F597100), a selective serotonin reuptake inhibitor which is used as an antidepressant. Uses A metabolite of Fluoxetine, a selective serotonin reuptake inhibitor which is used as an antidepressant. Uses A labelled metabolite of Fluoxetine, a selective serotonin reuptake inhibitor which is used as an antidepressant. (S)-Norfluoxetine synthesis Synthesis of (S)-Norfluoxetine from Norfluoxetine hydrochloride (S)-Norfluoxetine Preparation Products And Raw materials Raw materials Benzenepropanenitrile, β-[4-(trifluoromethyl)phenoxy]-, (βS)- (S)-3-Amino-1-phenyl-propan-1-ol (S)-Norfluoxetine 4-Fluorobenzotrifluoride 4-Chlorobenzotrifluoride Preparation Products (R)-Norfluoxetine (S)-Norfluoxetine Suppliers Global Suppliers ( 20) Canada        1China        14India        3United States        2Global        20 29128 58 126924-38-7 ((S)-Norfluoxetine) Related Search: Methyl-[(S)-3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine 3-(4-(Trifluoromethyl)phenoxy)propan-1-amine 1-Benzyloxy-4-trifluoromethyl-benzene (R)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine hydrochloride S-(+)-Fluoxetine hydrochloride (R)-Norfluoxetine (S)-Norfluoxetine (S)-3-PHENYL-3-(4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE Seproxetine [inn] Unii-25co3X0R31 (S)-Norfluoxetine 1-[(1S)-3-Amino-1-phenylpropoxy]-4-(trifluoromethyl)benzene Benzenepropanamine, γ-[4-(trifluoromethyl)phenoxy]-, (γS)- (3S)-3-Phenyl-3-[4-(Trifluoromethyl)Phenoxy]-1-Propanamine 126924-38-7 Aromatics Intermediates & Fine Chemicals Isotope Labelled Compounds Metabolites & Impurities Pharmaceuticals Amines

More Details:126924-38-7 SDS

126924-38-7Upstream product

• • 98-56-64-chlorobenzotrifluoride 
  • 130194-42-2(1S)-3-amino-1-phenyl-1-propanol 
  • 191729-88-1(S)-3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propionitrile 
  • 132203-26-0(S)-3-hydroxy-3-phenylpropanenitrile 
  • 402-45-94-hydroxybenzotrifluoride 
  • 191729-85-8(R)-2-Phenyl-2-(4-trifluoromethyl-phenoxy)-ethanol 
  • 191729-82-5(R)-Phenyl-(4-trifluoromethyl-phenoxy)-acetic acid (S)-1-methyl-2-oxo-2-pyrrolidin-1-yl-ethyl ester 
  • 20780-53-4(R)-Styrene oxide 
  • 402-44-84-Fluorobenzotrifluoride 
  • 83891-03-6norfluoxetine 
  • 878663-13-9(S)-1-phthalimido-3-(4-trifluormethyl-phenoxy)-3-phenyl-propane 
  • 100306-33-0(1R)-3-chloro-1-phenylpropanol 
  • 114446-51-4-(-)-1-chloro-3-phenyl-3-<4-(trifluoromethyl)phenoxy>propane 

• 114133-37-8(S)-N-methyl-3-amino-1

---

1. (S)-3-Phenyl-3- (4- (trifluoromethyl)phenoxy)propan-1-amine

   AABH303716C4-2.5MG Réf. du fournisseur: AA000TEZ-2.5MG 817,32 € Expédition sous 21 jour (s) – par un Aldrich Partner.
2. Cas 126924-38-7, (S)-3-PHENYL-3- (4-TRIFLUOROMETHYL …

   (S)-3-PHENYL-3- (4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE is a chiral compound that is a metabolite of Fluoxetine, a …

3. (S)-3-PHENYL-3- (4-TRIFLUOROMETHYL-PHENOXY) …

   TradingChem provides information about (S)-3-PHENYL-3- (4-TRIFLUOROMETHYL-PHENOXY)-PROPYLAMINE, ,CAS #: 126924 …

4. CAS RN 126924-38-7 | Fisher Scientific

   CAS: 126924-38-7 Nom chimique ou matériau: (S)-Norfluoxetine Poids de la formule: 295.1184 Formule InChI: …

5. CAS RN 126924-38-7 | Fisher Scientific

   CAS: 126924-38-7 Fórmula molecular: C16 H16 F3 N O Peso molecular (g/mol): 295.3 Sinónimo: Benzenepropanamine, γ- [4- …

6. Seproxetine (hydrochloride) – (3S)-3-phenyl-3-[4-(trifluoromethyl …

   Seproxetine (hydrochloride). C16H17O1N1Cl1F3. Synonyms: (3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine …

7. Seproxetine [inn] – 126924-38-7 – Catalog of Chemical Suppliers

   Supplier Description Reference capotchem (S)-3-Phenyl-3- (4-trifluoromethyl-phenoxy)-propylamine, NLT 98% … advtechind (S) …

8. (S)-Norfluoxetine | 126924-38-7

   (S)-Norfluoxetine is a labelled Fluoxetine (F597100) derivative,it is a stereoselective inhibitorof serotonin re-uptake and …

9. (S)-Norfluoxetine | 126924-38-7

   (S)-Norfluoxetine is a labelled Fluoxetine (F597100) derivative,it is a stereoselective inhibitorof serotonin re-uptake and …

10. (S)-Norfluoxetine, CAS 126924-38-7 (sc-208373) | Szabo-Scandic

    (S)-Norfluoxetine, CAS 126924-38-7 available from Santa Cruz Biotechnology at SZABO-SCANDIC. You can find out more about …