Buy Phencyclidine (phenylcyclohexyl piperidine) Cas 77-10-1

Phencyclidine or phenylcyclohexyl piperidine (PCP), also known in its use as a street drug as angel dust among other names, is a dissociative anesthetic mainly used recreationally for its significant mind-altering effects.^[1][4] PCP may cause hallucinations, distorted perceptions of sounds, and psychotic behavior.^[4][7][8] As a recreational drug, it is typically smoked, but may be taken by mouth, snorted, or injected.^[4][5][7] It may also be mixed with cannabis or tobacco.^[1][4]

Adverse effects may include paranoia, addiction, and an increased risk of suicide, as well as seizures and coma in cases of overdose.^[7] Flashbacks may occur despite stopping usage.^[8] Chemically, PCP is a member of the arylcyclohexylamine class.^[4][9][10] PCP works primarily as an NMDA receptor antagonist.^[9]

PCP is most commonly used in the US.^[11] While usage peaked in the US in the 1970s,^[12] between 2005 and 2011, an increase in visits to emergency departments as a result of the drug occurred.^[7] As of 2022, in the US, about 0.7% of 12th-grade students reported using PCP in the prior year, while 1.7% of people in the US over age 25 reported using it at some point in their lives.^[13]

Phencyclidine is used for its ability to induce a dissociative state.^[14]

Behavioral effects can vary by dosage. Low doses produce numbness in the extremities and intoxication, characterized by staggering, unsteady gait, slurred speech, bloodshot eyes, and loss of balance. Moderate doses (5–10 mg intranasal, or 0.01–0.02 mg/kg intramuscular or intravenous) will produce analgesia and anesthesia. High doses may lead to convulsions.^[15] The drug is often illegally produced under poorly controlled conditions; this means that users may be unaware of the actual dose they are taking.^[16]

Psychological effects include severe changes in body image, loss of ego boundaries, paranoia, and depersonalization. Psychosis, agitation and dysphoria, hallucinations, blurred vision, euphoria, and suicidal impulses are also reported, as well as occasional aggressive behavior.^{[17][18]: 48–49 [15]} PCP may induce feelings of strength, power, and invulnerability as well as a numbing effect on the mind.^[5]

Studies by the Drug Abuse Warning Network in the 1970s show that media reports of PCP-induced violence are greatly exaggerated and that incidents of violence are unusual and often limited to individuals with reputations for aggression regardless of drug use.^[18]: 48 Although uncommon, events of PCP-intoxicated individuals acting in an unpredictable fashion, possibly driven by their delusions or hallucinations, have been publicized.^[19] Other commonly cited types of incidents include inflicting property damage and self-mutilation of various types, such as pulling out one’s teeth.^{[18]: 48 [19]} These effects were not noted in its medicinal use in the 1950s and 1960s, however, reports of physical violence on PCP have often been shown to be unfounded.^[20][21]

Recreational doses of the drug also occasionally appear to induce a psychotic state, with emotional and cognitive impairment that resembles a schizophrenic episode.^[22][23] Users generally report feeling detached from reality.^[24]

Symptoms are summarized by the mnemonic device RED DANES: rage, erythema (redness of skin), dilated pupils, delusions, amnesia, nystagmus (oscillation of the eyeball when moving laterally), excitation, and skin dryness.^[25]