Buy Naphazoline (decongestant) Cas 835-31-4

Naphazoline is a medicine used as a decongestant, and a vasoconstrictor added to eye drops to relieve red eye. It has a rapid action in reducing swelling when applied to mucous membranes. It is a sympathomimetic agent with marked alpha adrenergic activity that acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion.

It was patented in 1934 and came into medical use in 1942.^[1]

Nasal decongestant.^[2]

Eye drops (brand names Clear Eyes, and Cleari) narrowing swollen blood vessels (ophthalmic arteries, and ophthalmic veins) to relieve red eye.^[2]

Temporary red eye can safely be treated when the cause of the redness is established (e.g. cannabis induced conjunctival vasodilation).^[3] However, continuous use is not recommended without knowing an underlying condition.

A few warnings and contraindications that apply to all naphazoline-containing substances intended for medicinal use are:

• Hypersensitivity to naphazoline
• Use in infants and children can result in central nervous system depression, leading to coma and marked reduction in body temperature
• Should be used with caution in patients with severe cardiovascular disease including cardiac arrhythmia and in patients with diabetes, especially those with a tendency toward diabetic ketoacidosis
• A possible association with stroke has been suggested.^[4]

• Extended use may cause rhinitis medicamentosa, a condition of rebound nasal congestion.

Known side-effect:^[5][6]

• Stinging
• Discomfort
• Irritation
• Increased red eyes
• Blurred vision
• Mydriasis
• Punctate keratitis
• Lacrimation (tears)
• Increased intraocular pressure