Buy Cyproheptadine ( Periactin) Cas 129-03-3

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Buy Cyproheptadine ( Periactin) Cas 129-03-3

Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine which is used to treat allergies.[2] In addition, it has a number of off-label uses, such as treatment of serotonin syndrome and insomnia.[7][8] The drug is taken orally.[2]

It is an antihistamine and hence acts as a histamine H1 receptor antagonist.[2] In addition to its antihistamine activity, cyproheptadine has anticholinergicantiserotonergicantidopaminergic, and local anesthetic properties.[2][7][9][10] These activities make cyproheptadine useful for various additional uses besides antihistamine indications.[7] As a first-generation antihistamine, cyproheptadine crosses the blood–brain barrier and can produce sedation.[9] The drug can also produce significant central anticholinergic effects at clinically used doses.[11][9]

Cyproheptadine was patented in 1959 and came into medical use in 1961.[12] In 2023, it was the 234th most commonly prescribed medication in the United States, with more than 1 million prescriptions.[13][14]

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