Buy Antipsychotics (neuroleptics) Cas 6104-71-8

Antipsychotics, previously known as neuroleptics^[1] and major tranquilizers,^[2] are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders.^[3][4] Together with mood stabilizers, they are also a mainstay in the treatment of bipolar disorder.^[5] Moreover, they are also used as adjuncts in the treatment of treatment-resistant major depressive disorder.

The use of antipsychotics may result in many unwanted side effects such as involuntary movement disorders, gynecomastia, impotence, weight gain and metabolic syndrome. Long-term use can produce adverse effects such as tardive dyskinesia, tardive dystonia, tardive akathisia, and brain tissue volume reduction. Withdrawal from antipsychotics can cause insomnia, tremors, and psychotic symptoms.^[6]

First-generation antipsychotics (e.g., chlorpromazine, haloperidol, etc.), known as typical antipsychotics, were first introduced in the 1950s, and others were developed until the early 1970s.^[7] Second-generation antipsychotics, known as atypical antipsychotics, arrived with the introduction of clozapine in the early 1970s followed by others (e.g., risperidone, olanzapine, etc.).^[8] Both generations of medication block receptors in the brain for dopamine, but atypicals block serotonin receptors as well. Third-generation antipsychotics were introduced in the 2000s and offer partial agonism, rather than blockade, of dopamine receptors.^[9] Neuroleptic, originating from Ancient Greek: νεῦρον (neuron) and λαμβάνω (take hold of)—thus meaning “which takes the nerve”—refers to both common neurological effects and side effects.^[10]