Buy 4-Methylthioamphetamine (para) Cas 14116-06-4

4-Methylthioamphetamine (4-MTA), also known as para-methylthioamphetamine (MTA), is a designer drug of the substituted amphetamine class developed in the 1990s by a team led by David E. Nichols, an American pharmacologist and medical chemist, at Purdue University. It acts as a non-neurotoxic highly selective serotonin releasing agent (SSRA) in animals.^[2][3][4] 4-MTA is the methylthio derivative of amphetamine.

4-MTA is a strong serotonin releaser similar to para-methoxyamphetamine (PMA), which can cause pronounced hyperthermia potentially resulting in organ failure and death.^{[5][6][7][8][better source needed]} Therefore, the major neuropharmacological effect is an increased release of serotonin, and the inhibition of serotonin uptake of monoamine oxidase A (MAO-A). The combination of the releasing of serotonin from neurons and the prevention of breaking this neurotransmitter down again, leads to dangerous serotonin syndrome. The serotonin syndrome is a hyper serotonergic state, which can become fatal and is a side effect of serotonergic drugs. The symptoms of serotonin syndrome caused by 4-MTA are described in the Report on the Risk Assessment of 4-MTA

Symptoms of the serotonin syndrome caused by 4-MTA

• Euphoria
• Drowsiness
• Sustained rapid eye movement
• Hyperreflexia – overreaction of the reflexes
• Agitation
• Restlessness
• Tachycardia – fast heart rate
• Headache
• Clumsiness
• Disorientation
• Intoxication – feeling drunk and dizzy
• Rigidity
• Rapid muscle contraction and relaxation in the ankle causing abnormal movements of the foot
• Muscle contraction and relaxation in the jaw
• Muscle twitching leading to hyperthermia
• Shivering
• High body temperature
• Sweating
• Altered mental status (including confusion and hypomania – a ‘happy drunk state’)