Order Methenolone acetate Cas 434-05-9

Order Methenolone acetate Cas 434-05-9

Methenolone acetate

Methenolone acetate structure

CAS No.: 434-05-9

Chemical Name:: Methenolone acetate

Synonyms: primobolan;METENOLONE ACETATE;nibal;sh567;sh567a;PriMo A;sq16496;pirmo a;NSC 74226;17-Acetate

CBNumber:: CB8446910

Molecular Formula:: C22H32O3

Molecular Weight:: 344.49

MDL Number:: MFCD00864181

MOL File:: 434-05-9.mol

TDS File:: TDS

Last updated:2026-07-22 17:56:16

Product description	Number	Pack Size	Price
Methenolone acetate	FM177344	1kg	$15881.3
Methenolone acetate	FM177344	2kg	$30250
Metenolone acetate 98%	Z238864	250MG	$380
Metenolone acetate 98%	Z238864	1G	$1135
Methenolone acetate 98+%	CD33000297	1g	$115
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Methenolone acetate Properties

Melting point	138-139°
Boiling point	419.57°C (rough estimate)
Density	1.0906 (rough estimate)
refractive index	1.5000 (estimate)
storage temp.	Store at -20°C
solubility	DMSO : ≥ 3.6 mg/mL (10.45 mM)
form	Solid
color	White to Off-White
InChI	InChI=1/C22H32O3/c1-13-11-16(24)12-15-5-6-17-18-7-8-20(25-14(2)23)21(18,3)10-9-19(17)22(13,15)4/h11,15,17-20H,5-10,12H2,1-4H3/t15-,17-,18-,19-,20-,21-,22-/s3
InChIKey	PGAUJQOPTMSERF-MQEWATRANA-N
SMILES	[C@]12([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC[C@@]1([H])CC(=O)C=C(C)[C@]21C)OC(=O)C \|&1:0,4,6,10,12,16,24,r\|
CAS DataBase Reference	434-05-9(CAS DataBase Reference)
FDA UNII	W75590VPKQ

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H302-H360-H351-H362
Precautionary statements	P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313

Methenolone acetate price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FM177344	Methenolone acetate	434-05-9	1kg	$15881.3	2026-06-04	Buy
Biosynth	FM177344	Methenolone acetate	434-05-9	2kg	$30250	2026-06-04	Buy
ACHEMBLOCK	Z238864	Metenolone acetate 98%	434-05-9	250MG	$380	2026-05-27	Buy
ACHEMBLOCK	Z238864	Metenolone acetate 98%	434-05-9	1G	$1135	2026-05-27	Buy
Crysdot	CD33000297	Methenolone acetate 98+%	434-05-9	1g	$115	2026-05-27	Buy

Methenolone acetate Chemical Properties, Uses, Production

Preparation

In a dry reaction flask, metenolone and acetic anhydride were mixed. Pyridine was then slowly added to the reaction mixture as an acid-binding agent and reaction solvent. The resulting reaction mixture was vigorously stirred at room temperature. The reaction progress was monitored by TLC or gas chromatography. After the starting material metenolone had completely reacted, the reaction mixture was slowly poured into an ice-water mixture. The reaction system was extracted multiple times with an organic solvent. All organic layers were combined and dried on anhydrous sodium sulfate. The desiccant was removed by filtration, and the resulting filtrate was concentrated under vacuum to remove volatile organic solvents. The residue was purified by silica gel column chromatography to obtain Methenolone acetate.

Description

Methenolone acetate (Brand name: Primobolan) is a synthetic, orally active anabolic-androgenic steroid and dihydrotestosterone (DHT) derivative. It can be used for the treatment of bone marrow disease and anemia. Methenolone acetate is known for its higher therapeutic efficiency and lower hepatic toxicity compared with its 17 alpha- alkylated analogs. However, it is frequently abused in human sports because of its capability of increasing muscle strength as well as promoting performance and aggressiveness. It is capable of enhancing performance in racehorses.

Chemical Properties

White Solid

Originator

Primobolan ,Schering ,W. Germany,1961

Uses

Methenolone acetate is an anabolic steroid. This is a controlled substance.

Definition

ChEBI: Methenolone acetate is a steroid ester.

Manufacturing Process

8.42 ml of methyl iodide are slowly added dropwise at room temperature with stirring in a nitrogen atmosphere to 3.067 g of magnesium turnings and 107 ml of absolute ether. After about 30 minutes, 185 ml of absolute tetrahydrofuran are slowly introduced and then liquid is distilled off until a boiling point of 62°C is reached. After cooling to room temperature, 613 mg of cuprous chloride are added and then 10 g of 1,4,6-androstatrien-17β-ol-3- one-17-acetate in 110 ml of tetrahydrofuran slowly introduced. After 30 minutes reaction time, the whole is cooled to 0C, the excess of Grignard reagent decomposed with saturated ammonium chloride solution, the product diluted with ether and the aqueous phase separated. The ethereal phase is washed consecutively with aqueous sodium thiosulfate solution, saturated ammonium chloride solution and water. It is dried over sodium sulfate and evaporated to dryness under vacuum. The residue is dissolved in 40 ml of pyridine and 20 ml of acetic anhydride and the solution kept for 16 hours at room temperature. It is then stirred into ice water and the precipitate filtered with suction, dried and recrystallized from isopropyl ether. 1α-Methyl-4,6- androstadien-17β-ol-3-one-17-acetate is obtained. MP 156°C to 157°C; [α]D25 = -33.8° (in CHCl3; c = 0.9). Yield 65-70% of the theoretical.
4.67 g of 1α-methyl-4,6-androstadien-17β-ol-3-one-17-acetate are dissolved in 273 ml of methanol and, after the addition of 350 mg of 10% palladium on calcium carbonate catalyst, hydrogenated until 1 mol equivalent of hydrogen has been taken up. After filtering off the catalyst, the solution is treated with 150 ml of 2N-hydrochloric acid and evaporated under vacuum to about 1/3 of the volume. The whole is then diluted with water and extracted with ether. The ethereal solution is washed with water until neutral, dried over sodium sulfate and evaporated. The crude product is heated on a steam bath for 90 minutes in 10 ml of pyridine and 10 ml of acetic anhydride. Extraction with ether is then carried out and the ethereal phase washed until neutral with water. The crude crystalline 1α-methyl-4-androsten-17β-ol-3-one-17- acetateobtained after drying and evaporation of the solution, melts at 122°C to 129°C. Yield 98% of the theoretical.
1α-Methyl-4-androsten-17β-ol-3-one-17-acetate when purified by recrystallization from isopropyl ether melts at 138°C to 139°C.

Therapeutic Function

17β-Hydroxy-1β-methyl-5α-androst-l-ene-3-one acetate

References

Ho, Emmie N. M., et al. “Metabolic studies of methenolone acetate in horses.” Analytica Chimica Acta 540.1(2005): 111-119.
https://en.wikipedia.org/wiki/Metenolone_acetate

Methenolone acetate Preparation Products And Raw materials

Raw materials

Iodomethane Magnesium Hydrogen

Chemical Name:(5S,8R,9S,10S,13S,14S,17S)-1,10,13-trimethyl-3-oxo-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-17-yl acetate

Shipping Temperature:Room Temperature

HSN Code:38229010

Country of Origin:India

Smiles:C[C@@]([C@@](C1)([H])CC2)(C(C)=CC1=O)[C@]3([H])[C@]2([H])[C@@](CC[C@@H]4OC(C)=O)([H])[C@]4(C)CC3

CHNS Ratio (%):C:76.70, H:9.36, N:0.00, S:0.00

Usage Note:Compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption.

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