Order Pyrrolidine tetrahydropyrrole (CAS 123-75-1)

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Order Pyrrolidine tetrahydropyrrole (CAS 123-75-1)

Order Pyrrolidine tetrahydropyrrole (CAS 123-75-1)

Buy Pyrrolidine Tetrahydropyrrole Online

Buy Pyrrolidine Tetrahydropyrrole Online . Pyrrolidine Dithiocarbamate, Ammonium Derivative, also known as Pyrrolidinedithiocarbamate, can be used for several biochemical applications like metal chelation. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.

Names Order Pyrrolidine Tetrahydropyrrole Online

Ammonium Pyrrolidinecarbodithioate  ; 1-Pyrrolidinecarbodithioic Acid Ammonium Salt

 

Chemical Properties Buy Pyrrolidine  Online

Density 0.8±0.1 g/cm3
Boiling Point 89.5±8.0 °C at 760 mmHg
Melting Point -63 °C
Molecular Formula C4H9N
Molecular Weight 71.121
Flash Point 2.8±0.0 °C
Exact Mass 71.073502
PSA 12.03000
LogP 0.37
Vapour density 2.45 (vs air)
Vapour  Pressure 58.6±0.2 mmHg at 25°C
Index of Refraction 1.428
Stability Stable; flammable. Incompatible with strong acids, strong oxidizing agents

CHEMICAL IDENTIFICATIONRTECS NUMBER : UX9650000
CHEMICAL NAME : Pyrrolidine
CAS REGISTRY NUMBER : 123-75-1
BEILSTEIN REFERENCE NO. : 0102395
LAST UPDATED : 199701DATA ITEMS CITED : 11
MOLECULAR FORMULA : C4-H9-N
MOLECULAR WEIGHT : 71.14
WISWESSER LINE NOTATION : T5MTJ

Safety Information  Pyrrolidine Tetrahydropyrrole

 

Symbol GHS02, GHS05, GHS07
Signal Word Danger
Hazard Statements H225-H302 + H332-H314
Precautionary Statements P210-P280-P305 + P351 + P338-P310
Personal Protective Equipment Face shields; full-face respirator (US);Gloves; Goggles; multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F:Flammable;C:Corrosive;
Risk Phrases R11;R20/21/22;R35
Safety Phrases S16-S26-S36/37/39-S45-S33
RIDADR UN 1922 3/PG 2
WGK Germany 2
RTECS UX9650000
Packaging Group II
Hazard Class 3
HS Code 2933990090
Synonyms  Pyrrolidine Tetrahydropyrrole
Tetrahydro pyrrole
Pyrrolidine [UN1922] [Flammable liquid]
Pyrrole, tetrahydro-
Tetramethyleneimine
Pyrrolidinepyrrolidine
Azolan
EINECS 204-648-7
1-Azacyclopentane
T5MTJ
Tetrahydropyrrole, Tetramethyleneimine
MFCD00005249
Pyrrolidine
Tetrahydropyrrole
Packing Factory Pyrrolidine Tetrahydropyrrole 

· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.

Factory Price Pyrrolidine liquid, Tetrahydropyrrole, Azolan wholesale  from china

wholesale Tetrahydro pyrrole
Factory price Pyrrolidine [UN1922] [Flammable liquid]
Order Pyrrole, tetrahydro- china
Tetramethyleneimine supplier
Pyrrolidinepyrrolidine dealer
Azolan EINECS 204-648-7
1-Azacyclopentane T5MTJ
Tetrahydropyrrole MFCD00005249
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Wholesale CAS 123-75-1

Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula (CH2)4NH. It is a cyclic secondary amine, also classified as a saturated heterocycle. It is a colourless liquid that is miscible with water and most organic solvents. It has a characteristic odor that has been described as “ammoniacal, fishy, shellfish-like”.[4] In addition to pyrrolidine itself, many substituted pyrrolidines are known.

Production and synthesis

Industrial production

Pyrrolidine is prepared industrially by the reaction of 1,4-butanediol and ammonia at a temperature of 165–200 °C and a pressure of 17–21 MPa in the presence of a cobalt- and nickel oxide catalyst, which is supported on alumina.[5]

 

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Pyrrolidine

Pyrrolidine Structure
CAS No.
123-75-1
Chemical Name:
Pyrrolidine
Synonyms
TETRAHYDROPYRROLE;Pyrrolidin;FEMA 2523;FEMA 3523;PRD;Azolidine;Prolamine;Tetrapyrrole;AZACYCLOPENTANE;Tetrahydropyrrol
CBNumber:
CB9852978
Molecular Formula:
C4H9N
Molecular Weight:
71.12
MOL File:
123-75-1.mol
MSDS File:
SDS
Modify Date:
6/23/2026 4:59:16 PM
Request For Quotation

Pyrrolidine Properties

Melting point -63 °C
Boiling point 87-88 °C/760 mmHg (lit.)
Density 0.852 g/mL at 25 °C (lit.)
vapor density 2.45 (vs air)
vapor pressure 128 mm Hg ( 39 °C)
refractive index n20/D 1.443(lit.)
FEMA 3523 | PYRROLIDINE
Flash point 37 °F
storage temp. Store below +30°C.
solubility water: miscible
form Liquid
pka 11.27(at 25℃)
color Colorless to Almost colorless
Odor at 0.10 % in propylene glycol. ammoniacal animal egg amine
PH 12.9 (100g/l, H2O, 20℃)
explosive limit 1.6-10.6%(V)
Odor Type ammoniacal
biological source synthetic
Water Solubility Miscible with alcohol, ether, chloroform and water.
Specific Heat Capacity Cp(liquid): 2.2 J/(g·K), at 25℃
Sensitive Air Sensitive
Merck 14,8015
JECFA Number 1609
BRN 102395
Henry’s Law Constant 4.2×100 mol/(m3Pa) at 25℃, Amoore and Buttery (1978)
Dielectric constant 8.3000000000000007
Stability Stable; flammable. Incompatible with strong acids, strong oxidizing agents.
InChI 1S/C4H9N/c1-2-4-5-3-1/h5H,1-4H2
InChIKey RWRDLPDLKQPQOW-UHFFFAOYSA-N
SMILES C1CCNC1
LogP 0.22 at 25℃
Surface tension 30.11mN/m at 293.15K
CAS DataBase Reference 123-75-1(CAS DataBase Reference)
NIST Chemistry Reference Pyrrolidine(123-75-1)
EPA Substance Registry System Pyrrolidine (123-75-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) Flame (GHS02)Corrosion (GHS05)Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS02,GHS05,GHS06,GHS08
Signal word Danger
Hazard statements H330-H301-H314-H370-H225
Precautionary statements P501-P260-P270-P240-P210-P233-P243-P241-P242-P271-P264-P280-P284-P370+P378-P308+P311-P303+P361+P353-P301+P330+P331-P363-P301+P310+P330-P304+P340+P310-P305+P351+P338+P310-P403+P233-P403+P235-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes F,T,C
Risk Statements 11-22-23-34-35-20/21/22-20/22-R35-R20/21/22-R11
Safety Statements 16-26-36/37/39-45-33-S45-S36/37/39-S26-S16
RIDADR UN 1922
WGK Germany 2
RTECS UX9650000
F 34
Autoignition Temperature 653 °F
TSCA TSCA listed
HS Code 2933 99 80
HazardClass 3
PackingGroup II
Storage Class 3 – Flammable liquids
Hazard Classifications Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 2
Skin Corr. 1A
Hazardous Substances Data 123-75-1(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 433 mg/kg
REACH Registrations Active
Limited Quantities 1.0 L (0.3 gallon) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
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Pyrrolidine price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) W352316 Pyrrolidine FG 123-75-1 1SAMPLE ₹5141.88 2022-06-14 Buy
Sigma-Aldrich(India) P73803 Pyrrolidine 99% 123-75-1 5ML ₹1948.5 2022-06-14 Buy
Sigma-Aldrich(India) W352316 Pyrrolidine FG 123-75-1 1KG ₹7588.33 2022-06-14 Buy
Sigma-Aldrich(India) P73803 Pyrrolidine 99% 123-75-1 100ML ₹2100.05 2022-06-14 Buy
Sigma-Aldrich(India) P73803 Pyrrolidine 99% 123-75-1 500ML ₹9915.7 2022-06-14 Buy

Pyrrolidine Chemical Properties,Uses,Production

Chemical Properties

Pyrrolidine appears as a colorless to pale yellow liquid with an ammonia-like odor. It is infinitely miscible with water and conventional organic solvents such as methanol, acetone, ether, and chloroform. It acts as a lachrymator.
Chemically, pyrrolidine behaves like a secondary amine in every respect. For example, it undergoes Leuckart –Wallach and Mannich reactions and is readily converted into an enamine. In the presence of a catalyst, such as platinum at 360°C or rhodium at 650°C, pyrrole is formed. In the presence of a copper catalyst, N-methylpyrrolidone is converted into N-methylpyrrolidine.

Physical properties

Pyrrolidine has a penetrating amine-type odor, reminiscent of ammonia and piperidine. It is easy to turn yellow when exposed to light or humid air, easily soluble in water and ethanol. It is nauseating and diffusive.

Occurrence

Reported found in beer, bread, wheat bread, salmon caviar, fish, milk, leaves and stalks of celery, Camembert cheese, Limburger cheese, Russian cheeses, tilsit cheese, other cheeses, caviar, raw fatty fish, beer, Finnish whiskey, white wine, red wine, coffee, radish, malt, roasted peanut, sweet corn and roasted barley.

Uses

Pyrrolidine is a flammable alkaline liquid that undergoes reactions typical of secondary amines. It is used to prepare pesticides and rubber accelerators and as a chemical intermediate (usually the hydrochloride form) in the pharmaceutical industry. There is relatively limited industrial exposure to this material.

Application

Pyrrolidine is a heterocyclic compound used as a building block in the synthesis of wide range of pharmaceutical compounds, namely matrix metalloprotein inhibitors (MMPIs) and aminopeptidase N inhibitors (APNIs). It has been used for the synthesis of N-benzoyl pyrrolidine from benzaldehyde via oxidative amination. It may be used as a catalyst for the synthesis of N-sulfinyl aldimines from carbonyl compounds and sulfonamides.
Pyrrolidine can also be used to synthesize:
Taddol-pyrrolidine phosphoramidite, a ligand for rhodium-catalyzed [2+2+2] cycloaddition of pentenyl isocyanate and 4- ethynylanisole.
H,4 PyrrolidineQuin-BAM (′PBAM′), a selective catalyst for the aza-Henry addition of nitroalkanes to aryl aldimines.
1,2,3,3a,4,9-Hexahydropyrrolo[2,1-b]quinazoline by reacting with o-aminobenzaldehyde.

Preparation

Pyrrolidine is formed by reduction of pyrrole. Via overall 5-endo-trig cyclizations of homoallylic tosylamides. Pyrrolidine can be produced from butanediol and ammonia, e.g., over an aluminum thorium oxide catalyst at 300°C or over a nickel catalyst at 200°C and 20 MPa under hydrogenation conditions. It can also be produced from THF and ammonia over aluminum oxide at 275-375°C.

Definition

ChEBI: Pyrrolidine is a cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family. It is a saturated organic heteromonocyclic parent, a member of pyrrolidines and an azacycloalkane. It is a conjugate base of a pyrrolidinium ion.

General Description

Pyrrolidine is a saturated heterocycliccompound having one nitrogenatom in a five-membered ring. It is a colorless to pale yellow liquid with an ammonia-like odor. It is found in certain plants andthe ring structure is present in manyalkaloids. Flash point 37°F. Density 0.85 g / cm3. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion.

Air & Water Reactions

Highly flammable. Very soluble in water.

Reactivity Profile

Tetrahydro pyrrole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. An explosion occurred when a mixture of Tetrahydro pyrrole, benzaldehyde, and propionic acid was heated in an attempt to form porphyrins.

Hazard

Flammable, dangerous fire risk. Toxic by ingestion and inhalation.

Health Hazard

The acute toxicity of pyrrolidine is moderateon test animals. It is somewhat less toxicthan pyrrole. The vapors are an irritant tothe eyes and respiratory tract. The liquid iscorrosive to the skin. Contact with the eyescan cause damage. The oral LD50 value inrats is 300 mg/kg, while the inhalation LC50value in mice is 1300 mg/m3/2 h (NIOSH1986).

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Poison by ingestion and intravenous routes. Moderately toxic by inhalation. Dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits hghly toxic fumes of NOx.

Purification Methods

Dry pyrrolidine with BaO or sodium, then fractionally distil it, under N2, through a Todd column (p 11) packed with glass helices. [Beilstein 20 H 159, 20 I 36, 20 II 79, 20 III/IV 2072, 20/1 V 162.]

Pyrrolidine Preparation Products And Raw materials

Raw materials

Preparation Products

FAQs: Pyrrolidine

 

 

 

 

 

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    • CAS RN: 123-75-1
    • MDL Number: MFCD00005249
    • EC Number: 204-648-7
    • Storage Temperature: +20°C
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    • Boiling point: 87-88 °C/760 mmHg (lit.)
    • Melting point: 63 °C
    • Density: 0.852 g/mL at 25 °C (lit.)
    • vapor density: 2.45 (vs air)
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