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3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (tablet form), and molly (crystal form),^[19][20] is an entactogen with stimulant and minor psychedelic properties.^[17][21][22]

MDMA was first synthesized in 1912 by Merck chemist Anton Köllisch.^[23] It was used to enhance psychotherapy beginning in the 1970s and became popular as a street drug in the 1980s.^[24][25] MDMA is commonly associated with dance parties, raves, and electronic dance music.^[26] Tablets sold as ecstasy may be mixed with other substances such as ephedrine, amphetamine, and methamphetamine.^[24] In 2016, about 21 million people between the ages of 15 and 64 used ecstasy (0.3% of the world population).^[27] In the United States, as of 2017, about 7% of people have used MDMA at some point in their lives and 0.9% have used it in the last year.^[28] The lethal risk from one dose of MDMA is estimated to be from 1 death in 20,000 instances to 1 death in 50,000 instances.

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The purported pharmacological effects that may be prosocial include altered sensations, increased energy, empathy, and pleasure.^[22][24] When taken by mouth, effects begin in 30 to 45 minutes and last three to six hours.^[13][25] Short-term adverse effects include grinding of the teeth, blurred vision, sweating, and a rapid heartbeat,^[24] and extended use can also lead to addiction, memory problems, paranoia, and difficulty sleeping. Deaths have been reported due to increased body temperature and dehydration. MDMA acts primarily by increasing the release of the neurotransmitters serotonin, dopamine, and norepinephrine in parts of the brain.^[24][25] It belongs to the substituted amphetamine classes of drugs.^[10][30] MDMA is structurally similar to mescaline (a psychedelic), methamphetamine (a stimulant), as well as endogenous monoamine neurotransmitters such as serotonin, norepinephrine, and dopamine.^[31]

MDMA has limited approved medical uses in a small number of countries,^[32] but is illegal in most jurisdictions.^[33] MDMA-assisted psychotherapy is a promising and generally safe treatment for post-traumatic stress disorder when administered in controlled therapeutic settings.^[34][35] In the United States, the Food and Drug Administration (FDA) has given MDMA breakthrough therapy status (though there no current clinical indications in the US).^[36] Canada has allowed limited distribution of MDMA upon application to and approval by Health Canada.^[37] In Australia, it may be prescribed in the treatment of PTSD by specifically authorised psychiatrists.^[38]

MDMA is often considered the drug of choice within the rave culture and is also used at clubs, festivals, and house parties.^[15] In the rave environment, the sensory effects of music and lighting are often highly synergistic with the drug. The psychedelic amphetamine quality of MDMA offers multiple appealing aspects to users in the rave setting. Some users enjoy the feeling of mass communion from the inhibition-reducing effects of the drug, while others use it as party fuel because of the drug’s stimulatory effects.^[39] MDMA is used less often than other stimulants, typically less than once per week.^[40]

MDMA is sometimes taken in conjunction with other psychoactive drugs such as LSD,^[41] psilocybin mushrooms, 2C-B, and ketamine. The combination with LSD is called “candy-flipping”.^[41] The combination with 2C-B is called “nexus flipping”. For this combination, most people take the MDMA first, wait until the peak is over, and then take the 2C-B.^[42]

MDMA is often co-administered with alcohol, methamphetamine, and prescription drugs such as SSRIs with which MDMA has several drug-drug interactions.^[43][44][45] Three life-threatening reports of MDMA co-administration with ritonavir have been reported;^[46] with ritonavir having severe and dangerous drug-drug interactions with a wide range of both psychoactive, anti-psychotic, and non-psychoactive drugs.^[47]

As of 2023, MDMA therapies have only been approved for research purposes, with no widely accepted medical indications,^[10][48][49] although this varies by jurisdiction. Before it was widely banned, it saw limited use in psychotherapy.^[8][10][50] In 2017 the United States Food and Drug Administration (FDA) granted breakthrough therapy designation for MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD).^[51][52]

Some researchers have proposed that psychedelics in general may act as active “super placebos” used for therapeutic purposes.^[53][54]

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Product Quantity	Price
150 Pills	$250

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MDMA, chemically identified as 3,4-methylenedioxymethamphetamine, is a widely recognized compound in the field of analytical chemistry and research. Its unique molecular structure, represented by the chemical formula C₁₁H₁₅NO₂, with a CAS number typically around 42542-10-9 for its hydrochloride salt, makes it a subject of extensive study. Commonly referred to by its street names, Ecstasy or Molly, for research purposes, it is vital to focus on its pure chemical form and characteristics. At Chemsfine, we supply Top Quality MDMA Ecstasy Molly, ensuring researchers receive a product with verified purity and consistent composition essential for accurate experimental results. This commitment helps uphold the integrity of scientific investigations across various disciplines. Our compounds are rigorously tested to guarantee that they meet the highest industry-grade standards for purity and authenticity.

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• Analytical Reference Standards: Utilized as a benchmark for quantitative analysis in forensic toxicology and drug detection.
• Pharmacological Research: Essential for studying its effects on neurotransmitter systems and potential therapeutic applications under strict scientific protocols.
• Metabolism Studies: Used to investigate pharmacokinetic profiles and metabolic pathways in vitro.
• Toxicological Screening: Employed in studies to understand its safety profile and potential adverse effects at controlled dosages.
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For your convenience, here is a detailed overview of the MDMA (Ecstasy Molly) product available from Chemsfine, highlighting key specifications that confirm its suitability for rigorous research and analytical purposes.

Specification	Detail
Chemical Name	3,4-Methylenedioxymethamphetamine
Common Names	MDMA, Ecstasy, Molly
Chemical Formula	C11H15NO2
CAS Number	42542-10-9 (HCl salt)
Purity (Typical)	>98% (verified by CoA)
Appearance	Crystalline powder or pressed pills
Standard Offering	150 Pills = $250

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MDMA, chemically known as 3,4-methylenedioxymethamphetamine, is a synthetic compound with a distinctive chemical structure. Its formula is C₁₁H₁₅NO₂, and it has a CAS number of 42542-10-9. As a product, MDMA is recognized for its unique properties that make it a subject of various scientific inquiries. Our offerings include top quality MDMA Ecstasy, provided in a form suitable for research and analytical applications. It’s crucial for researchers and laboratories to utilize substances that are accurately characterized and consistently pure.

Product Specifications: MDMA Ecstasy

Characteristic	Detail
Chemical Name	3,4-Methylenedioxymethamphetamine
Common Name	MDMA, Ecstasy
Chemical Formula	C11H15NO2
CAS Number	42542-10-9
Purity Grade	High Purity (Laboratory Grade)
Physical Form	Crystal or Powder

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1. 3,4-METHYLENEDIOXYMETHAMPHETAMINE | 42542-10-9

   May 28, 2026 · (+/-)-3,4-METHYLENEDIOXYMETHAMPHETAMINE (CAS 42542-10-9) information, including chemical properties, …

   • Boiling point: bp0.4 100-110°
   • Flash point: 9℃

   • Density: 1.100±0.06 g/cm3 (Predicted)
   • storage temp.: 2-8°C

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   3,4-Methylenedioxymethamphetamine

   Base Information

   • Chemical Name:3,4-Methylenedioxymethamphetamine
   • CAS No.:42542-10-9
   • Deprecated CAS:69610-10-2,54946-52-0
   • Molecular Formula:C11H15NO2
   • Molecular Weight:193.246
   • Hs Code.:2932999099
   • UNII:KE1SEN21RM
   • DSSTox Substance ID:DTXSID90860791
   • Nikkaji Number:J276.360E
   • Wikipedia:MDMA
   • Wikidata:Q69488
   • NCI Thesaurus Code:C61081
   • Pharos Ligand ID:QSU2N2ZPKBBG
   • Metabolomics Workbench ID:52856
   • ChEMBL ID:CHEMBL43048
   • Mol file:42542-10-9.mol

   

   Synonyms:Ecstasy (Drug);Hydrochloride, N-Methyl-3,4-methylenedioxyamphetamine;MDMA;Methylenedioxymethamphetamine;N Methyl 3,4 methylenedioxyamphetamine;N Methyl 3,4 methylenedioxyamphetamine Hydrochloride;N-Methyl-3,4-methylenedioxyamphetamine;N-Methyl-3,4-methylenedioxyamphetamine Hydrochloride

    This product is a nationally controlled contraband, and the Lookchem platform doesn’t provide relevant sales information.

   Chemical Property of 3,4-Methylenedioxymethamphetamine

   Chemical Property:

   • Vapor Pressure:0.000272mmHg at 25°C 
   • Boiling Point:283.39 °C at 760 mmHg 
   • PKA:10.32±0.10(Predicted) 
   • Flash Point:113.23 °C 
   • PSA：30.49000 
   • Density:1.1 g/cm³ 
   • LogP:1.95660 
   • Storage Temp.:2-8°C 
   • XLogP3:2.2
   • Hydrogen Bond Donor Count:1
   • Hydrogen Bond Acceptor Count:3
   • Rotatable Bond Count:3
   • Exact Mass:193.110278721
   • Heavy Atom Count:14
   • Complexity:186

   Purity/Quality:

   Safty Information:

   • Pictogram(s):F,T 
   • Hazard Codes:F,T 
   • Statements:11-23/24/25-39/23/24/25 
   • Safety Statements:7-16-36/37-45 

   MSDS Files:

   SDS file from LookChem

   Total 1 MSDS from other Authors

   Useful:

   • Canonical SMILES:CC(CC1=CC2=C(C=C1)OCO2)NC
   • Recent ClinicalTrials:Randomized Placebo-controlled Study of MDMA-assisted Therapy in People With PTSD – Israel
   • Recent EU Clinical Trials:An Open- Label, Phase 2, Multicenter Feasibility Study if Manualized MDMA-Assisted Psychotherapy with an fMRI sub-study Assessing Changes in Brain Activity in Subjects with Posttraumatic Stress Disorder.
   Technology Process of 3,4-Methylenedioxymethamphetamine

   There total 19 articles about 3,4-Methylenedioxymethamphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

   synthetic route:

   Reference yield: 85.0%

   

   1616297-03-0(R)-ethyl 1-(benzo[d][1,3]dioxol-5-yl)propan-2-ylcarbamate

   

   

   42542-10-9,66142-89-0,69610-10-2,81262-70-6,54946-52-0(-)-3,4-Methylenedioxymethamphetamine

   Guidance literature:

   With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Reflux;

   DOI:10.1016/j.ejmech.2014.04.044

   Reference yield: 78.0%

   

   4676-39-51-(1,3-benzodioxol-5-yl)-2-propanone

   

   

   74-89-5methylamine

   

   

   42542-10-9,54946-52-03,4-methylenedioxymethamphetamine

   Guidance literature:

   1-(1,3-benzodioxol-5-yl)-2-propanone; methylamine; In ethanol; water; at 20 ℃; for 1h;

   With hydrogen; platinum(IV) oxide; In ethanol; water; for 3.5h; under 2896.11 Torr; Further stages.;

   DOI:10.1021/ac702559s

   Reference yield:

   

   (R)-(+)-N-formyl-1-(1,3-benzodioxol-5-yl)-2-propanamine

   

   

   42542-10-9,66142-89-0,69610-10-2,81262-70-6,54946-52-0(-)-3,4-Methylenedioxymethamphetamine

   Guidance literature:

   With lithium aluminium tetrahydride; In diethyl ether; for 4h; Yield given; Heating;

   DOI:10.1021/jm00160a035
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4. Methylenedioxymethamphetamine | 42542-10-9 – ChemicalBook

   May 28, 2026 · Methylenedioxymethamphetamine (CAS 42542-10-9) information, including chemical properties, structure, melting …

   • Boiling point: bp0.4 100-110°
   • Flash point: 9℃

   • Density: 1.100±0.06 g/cm3 (Predicted)
   • storage temp.: 2-8°C
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