Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8

Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8

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Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8

3,4-Methylenedioxy-N-ethylamphetamine (MDEA; also called MDE and colloquially, Eve) is an empathogenic psychoactive drug. MDEA is a substituted amphetamine and a substituted methylenedioxyphenethylamine. MDEA acts as a serotonin, norepinephrine, and dopamine releasing agent and reuptake inhibitor.[3][1][4]

Possession of MDEA is illegal in most countries. Some limited exceptions exist for scientific and medical research.

Uses

Medical

MDEA currently has no accepted medical uses.

Recreational

MDEA is used recreationally in a similar manner to MDMA (also called ecstasy), however the subjective effects of MDEA are milder and shorter lasting.[1][5] Alexander Shulgin reported it to be stoning in high doses.[3] Most frequently consumed orally, recreational doses of MDEA are in the range 100 to 200 mg. Infrequently, MDEA is an adulterant of ecstasy pills. Studies conducted in the 1990s found MDEA present in approximately four percent of ecstasy tablets.[1]

Adverse effects

Reported adverse effects from MDEA include the following:

Overdose

Reported overdose symptoms of MDEA include the following:

3,4-Methylenedioxy-N-ethylamphetamine

Base Information
  • Chemical Name:3,4-Methylenedioxy-N-ethylamphetamine
  • CAS No.:82801-81-8
  • Deprecated CAS:14089-52-2,116861-63-3
  • Molecular Formula:C12H17NO2
  • Molecular Weight:207.272
  • Hs Code.:
  • European Community (EC) Number:804-304-1
  • UNII:ML1I4KK67B
  • DSSTox Substance ID:DTXSID70860971
  • Nikkaji Number:J1.191.663E,J263.855J
  • Wikipedia:3,4-Methylenedioxy-N-ethylamphetamine
  • Wikidata:Q223011
  • Metabolomics Workbench ID:146214
  • ChEMBL ID:CHEMBL126279
  • Mol file:82801-81-8.mol
3,4-Methylenedioxy-N-ethylamphetamine

Synonyms:(+–)-N-ethyl-alpha-methyl-3,4-(methylenedioxy)phenethylamine;(R)-3,4-methylenedioxyethylamphetamine;(R)-isomer of 3,4-methylenedioxyethamphetamine;(R)-methylenedioxyethylamphetamine;(R,S)-N-ethyl-3,4-methylenedioxyamphetamine;(S)-3,4-methylenedioxyethylamphetamine;(S)-isomer of 3,4-methylenedioxyethamphetamine;(S)-methylenedioxyethylamphetamine;1,3-benzodioxole-5-ethanamine, N-ethyl-alpha-methyl-;1,3-benzodioxole-5-ethanamine, N-ethyl-alpha-methyl-, hydrochloride (1:1);3,4-methylenedioxyethamphetamine;3,4-methylenedioxyethylamphetamine;3,4-methylenedioxyethylamphetamine hydrochloride;D-3,4-methylenedioxyethylamphetamine;EVE (amphetamine);HCl of 3,4-methylenedioxyethamphetamine;MDE (-)-;MDE hydrochloride;MDE, (+)-;MDEA;MDEA hydrochloride;methylenedioxyethamphetamine;methylenedioxyethamphetamine hydrochloride;N-ethyl-3,4-methylenedioxyamphetamine;N-ethyl-MDA;N-MDE

 This product is a nationally controlled contraband, and the Lookchem platform doesn’t provide relevant sales information.

Chemical Property of 3,4-Methylenedioxy-N-ethylamphetamine
Chemical Property:
  • Appearance/Colour:white crystalline powder 
  • Vapor Pressure:0.00117mmHg at 25°C 
  • Melting Point:140-145 °C 
  • Refractive Index:1.53 
  • Boiling Point:299.8 °C at 760 mmHg 
  • PKA:10.34±0.19(Predicted) 
  • Flash Point:122.1 °C 
  • PSA：30.49000 
  • Density:1.078 g/cm3 
  • LogP:2.34670 
  • Storage Temp.:2-8°C 
  • XLogP3:2.5
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:4
  • Exact Mass:207.125928785
  • Heavy Atom Count:15
  • Complexity:198
Purity/Quality:
Safty Information:
  • Pictogram(s):Human systemic effects. 
  • Hazard Codes:Xi,T,F 
  • Statements:36/37/38-39/23/24/25-23/24/25-11 
  • Safety Statements:26-36-45-36/37-16-7 
MSDS Files:
SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CCNC(C)CC1=CC2=C(C=C1)OCO2
  • UsesMethylenedioxyethamphetamine is a illegal psychoactive substance.
Technology Process of 3,4-Methylenedioxy-N-ethylamphetamine

There total 6 articles about 3,4-Methylenedioxy-N-ethylamphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

1-(1,3-benzodioxol-5-yl)-2-propanone
4676-39-51-(1,3-benzodioxol-5-yl)-2-propanone
ethylamine
75-04-7,85404-22-4ethylamine
3,4-methylenedioxyethylamphetamine
14089-52-2,82801-81-8,114612-26-9,114612-27-03,4-methylenedioxyethylamphetamine
Guidance literature:
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
Buy 3-4-Methylenedioxy-N-ethylamphetamine (MDEA) Cas 82801-81-8
With sodium cyanoborohydride;

Reference yield:

3,4-methylenedioxyamphetamine
4764-17-43,4-methylenedioxyamphetamine
3,4-methylenedioxyethylamphetamine
14089-52-2,82801-81-8,114612-26-9,114612-27-03,4-methylenedioxyethylamphetamine
Guidance literature:
Multi-step reaction with 2 steps
1: 58 percent / pyridine / 18 h / Ambient temperature
2: LiAlH4 / tetrahydrofuran / 72 h / Heating
With pyridine; lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1002/jps.2600690220

Reference yield:

1-(1,3-benzodioxol-5-yl)-2-propanone
4676-39-51-(1,3-benzodioxol-5-yl)-2-propanone
3,4-methylenedioxyethylamphetamine
14089-52-2,82801-81-8,114612-26-9,114612-27-03,4-methylenedioxyethylamphetamine
Guidance literature:
Multi-step reaction with 3 steps
1: NaBH3CN / methanol / 36 h / Ambient temperature; neutral pH
2: 58 percent / pyridine / 18 h / Ambient temperature
3: LiAlH4 / tetrahydrofuran / 72 h / Heating
With pyridine; lithium aluminium tetrahydride; sodium cyanoborohydride; In tetrahydrofuran; methanol;

DOI:10.1002/jps.2600690220

upstream raw materials:
1-(1,3-benzodioxol-5-yl)-2-propanone

ethanamine hydrochloride

ethylamine

N-[1-methyl-2-(3,4-methylenedioxyphenyl)ethyl]acetamide

Downstream raw materials:
3,4-methylenedioxyamphetamine
Classification Analytical chemistry >> Standard >> Standard material
Name 3,4-Methylenedioxy-N-ethylamphetamine
Synonyms N-Ethyl-1-(3,4-methylenedioxyphenyl)-2-propylamine
Molecular Structure 3,4-Methylenedioxy-N-ethylamphetamine molecular structure (CAS 82801-81-8)
Molecular Formula C12H17NO2
Molecular Weight 207.27
CAS Registry Number 82801-81-8
EC Number 804-304-1
Safety Data
Hazard Classification
   Details
Hazard Class Category Code Hazard Statement
Eye irritation Eye Irrit. 2 H319
Skin irritation Skin Irrit. 2 H315
Specific target organ toxicity – single exposure STOT SE 3 H335
Controlled Substance DEA Drug Code Number: 7404   Details
CSA Schedule: I
Narcotics? No
Market Analysis Reports

Interactions

See also: MDMA § Interactions, Trip killer § Antidotes of other hallucinogens, and MDMA/citalopram

Chemistry

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    • Hazard statements: H225-H301+H311+H331-H370
    • Signal word: Danger
    • Precautionary statements: P210-P260-P280-P301+P310-P311
    • Symbol (GHS): GHS02,GHS06,GHS08

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