Buy 3-4-Methylenedioxyamphetamine (MDA) Cas 4764-17-4
3,4-Methylenedioxyamphetamine (MDA) is an entactogen, stimulant, and psychedelic drug of the amphetamine and MDxx families that is encountered mainly as a recreational drug.[4][5][6] It is usually taken orally.[4][6]
In terms of its pharmacology, MDA is a serotonin–norepinephrine–dopamine releasing agent (SNDRA) and a serotonin 5-HT2 receptor agonist, including of the serotonin 5-HT2A receptor.[4] It has a duration of 5 to 8 hours or around 6 hours typically.[4][3][2]
MDA has a long history of psychotherapeutic and recreational use that predates that of MDMA, dating back to at least the mid-1960s.[4][7][5] It has been described as the first entactogen.[3] MDA has also been described as probably the most popular analogue of MDMA.[7] In most countries, the drug is a controlled substance and its possession and sale are illegal.
Use and effects
MDA is bought, sold, and used as a recreational drug due to its enhancement of mood and empathy.[8] It produces MDMA-like effects, including entactogenic and stimulant effects, as well as mild psychedelic effects.[3][9][10][2]
The dose range of MDA given in Alexander Shulgin‘s book PiHKAL (Phenethylamines I Have Known and Loved) and other sources is 80 to 160 mg.[6][4] A wider recreational dose range for MDA of 20 to 200 mg or more, with a typical dose estimate of 90 mg, has also been reported.[11] The dose range of MDA is very similar to that of MDMA.[6][4][11][3]
The effects of MDA include euphoria, empathy, emotional amplification, relaxation, feeling at peace with the world, increased introspection, self-awareness, and acceptance, authenticity, clarity of thought, a desire to communicate with others and relate personal issues, and emotional bonding with others.[4][12][13] These effects led to MDA being called the “love drug” or “hug drug”.[12][6] MDA also produces mild psychedelic effects, including brightened colors, closed-eye visuals or complex mental imagery, synaesthesia, and rarely mild hallucinations.[4][3] It does not produce profound sensory disruption or overt hallucinations.[12][13] In any case, the drug has still been found to produce mystical or spiritual experiences.[9][3]
MDA shares most of MDMA’s qualitative and emotional effects, including entactogenic and stimulant effects.[4][13][3] However, it has been said to be slightly less stimulating than MDMA.[4][3] Conversely, a clinical study found that it was more stimulating than MDMA.[2] In addition, MDA’s hallucinogenic effects are much greater than those of MDMA, although still less than those of classical psychedelics like psilocybin.[4][12][3][2] Another difference between the two drugs is that MDA appears to produce a more introverted and emotionally intense prosocial state, while MDMA encourages a more extroverted and gregarious prosocial state.[3] MDA produces more negative “bad drug effects” and fear than MDMA.[2]
Besides its psychoactive effects, MDA produces sympathomimetic effects such as increased heart rate and blood pressure, among other physiological effects.[7][13][3]
In terms of the individual enantiomers of MDA, (R)-MDA produces psychedelic effects and some entactogenic effects, while (S)-MDA is non-hallucinogenic, produces similar entactogenic effects as the racemate, and has considerable stimulant effects.[12][13][6] High doses of enantiopure (R)-MDA, in the range of 120 to 200 mg, are described as closely resembling the effects of LSD, for instance doses of 200 to 400 μg.[13][14] Enantiopure (R)-MDA at high doses produces more robust psychedelic effects than typical doses of racemic MDA.[13][14][6]
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