Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. Although generally considered sedating, diphenhydramine can cause paradoxical central nervous system stimulation in some individuals, particularly at higher doses. This may manifest as agitation, anxiety, or restlessness rather than sedation.[15][16] It is a first-generation H1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.[17][2] Diphenhydramine is also a potent anticholinergic.[18] It is mainly used to treat allergies, insomnia, and symptoms of the common cold. It is also less commonly used for tremors in parkinsonism, and nausea.[17] It is taken by mouth, injected into a vein, injected into a muscle, or applied to the skin.[17] Maximal effect is typically around two hours after a dose, and effects can last for up to seven hours.[17]
Common side effects include sleepiness, poor coordination, and an upset stomach.[17] There is no clear risk of harm when used during pregnancy; however, use during breastfeeding is not recommended.[19]
It was developed by George Rieveschl and put into commercial use in 1946.[20][21] It is available as a generic medication.[17] In 2023, it was the 294th most commonly prescribed medication in the United States, with more than 700,000 prescriptions.[22][23]
Its sedative and deliriant effects have led to some cases of recreational use.
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Buy Diphenhydramine (Benadryl) Cas 58-73-1
Medical uses
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Diphenhydramine is a first-generation antihistamine used to treat several conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms.[25][26] Diphenhydramine also has local anesthetic properties, and has been used as such in people allergic to common local anesthetics such as lidocaine.[27]
Allergies
Diphenhydramine is effective in the treatment of allergies.[28] As of 2007, it was the most commonly used antihistamine for acute allergic reactions in the emergency department.[29]
By injection, it is often used in addition to epinephrine for anaphylaxis,[30] although as of 2007 its use for this purpose had not been properly studied.[31] Its use is only recommended once acute symptoms have improved.[28]
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Topical formulations of diphenhydramine are available, including creams, lotions, gels, sprays, and eye drops. These are used to relieve itching and have the advantage of causing fewer systemic effects (such as drowsiness) than oral forms.
| Keywords: | PM 255, PM255, Dabylen, PM-255, Syntedril, Debendrin |
| Supplier: | TargetMol |
| Supplier-Nr: | T21419 |
Properties
| MW: | 255.35 D |
| Formula: | C17H21NO |
Database Information
| CAS : | 58-73-1| Matching products |
| Protein Atlas Nr. : | Biochemicals/Chemicals |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
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Oct 6, 2015 · Diphenhydramine (CAS 58-73-1) information, including chemical properties, structure, melting point, boiling point, …
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