Buy Piracetam (myoclonus) Cas 7491-74-9

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Buy Piracetam (myoclonus) Cas 7491-74-9

Piracetam is a drug that has efficacy in cognitive disordersvertigo, cortical myoclonusdyslexia, and sickle cell anemia; sources differ on its usefulness for dementia.[3][4][5] Piracetam is sold as a medication in many European countries. Piracetam in the United States is not approved for general use.[6]

Piracetam is in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It is a cyclic derivative of the neurotransmitter GABA[4] and shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid. Related drugs include the anticonvulsants levetiracetam and brivaracetam, and the putative nootropics aniracetam and phenylpiracetam.

Efficacy

Dementia

A 2001 Cochrane review concluded that there was not enough evidence to support piracetam for dementia or cognitive problems.[5] A 2005 review found some evidence of benefit in older subjects with cognitive impairment.[4] In 2008, a working group of the British Academy of Medical Sciences noted that many of the trials of piracetam for dementia were flawed.[7]

There is insufficient evidence of piracetam as a treatment for vascular dementia.[8]

Depression and anxiety

Some sources suggest that piracetam’s overall effect on lowering depression and anxiety is higher than on improving memory.[9] However, depression is reported to be an occasional adverse effect of piracetam.[10]

Attention deficit hyperactivity disorder (ADHD)

Several clinical trials have looked at piracetam’s efficacy as a treatment for ADHD. Many of these have found that the drug fails to deliver the same therapeutic effects as current standard treatments for the disorder.[11][unreliable source?] However, more than one study has found piracetam to be highly synergistic with standard ADHD therapies, accelerating and potentiating their therapeutic effects. One 2008 clinical trial found that the combination of piracetam and atomoxetine was more effective than atomoxetine alone.[12]

While piracetam may be an effective adjuvant therapy for ADHD (when used with specific medications), there is no evidence that it is effective when used in isolation.

Other

Piracetam may facilitate the deformability of erythrocytes in capillaries which is useful for cardiovascular disease.[4][3]

Peripheral vascular effects of piracetam have suggested its use potential for vertigodyslexiaRaynaud’s phenomenon and sickle cell anemia.[4][3] There is no evidence to support piracetam’s use in sickle cell crisis prevention[13] or for fetal distress during childbirth.[14] There is no evidence for benefit of piracetam with acute ischemic stroke,[15] though there is debate as to its utility during stroke rehabilitation.[16][17]

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