Buy PS75 (analgesic) Cas 2925328-43-2

PS75 is an experimental analgesic drug which acts as a functionally selective alpha-2A (α_2A) adrenergic agonist, with a K_i of 8.2nM and an EC₅₀ of 4.8nM at the α_2A-adrenergic receptor. In animal studies it was found to produce analgesia but without the sedation typical of older drugs acting at this target such as dexmedetomidine. While PS75 itself is unlikely to be developed for medical use, the successful separation of analgesia from sedative effects makes it likely that related compounds may be developed as non-sedating, non-opioid analgesic medications.^[1]

is an experimental analgesic drug which acts as a functionally selective alpha-2A (α_2A) adrenergic agonist, with a K_i of 8.2nM and an EC₅₀ of 4.8nM at the α_2A-adrenergic receptor. In animal studies it was found to produce analgesia but without the sedation typical of older drugs acting at this target such as dexmedetomidine. While PS75 itself is unlikely to be developed for medical use, the successful separation of analgesia from sedative effects makes it likely that related compounds may be developed as non-sedating, non-opioid analgesic medications.^[1]